Japan researchers target degenerative eye disease with gene therapy

Keio University-linked startup launches clinical trials of retina treatment

20250213N Keio Kurihara

Toshihide Kurihara, associate professor of ophthalmology at Keio University, speaks on Feb. 13 about the start of clinical trials. (Photo by Noriaki Koshikawa)

NORIAKI KOSHIKAWA

TOKYO -- Researchers from Japan's Keio University and elsewhere announced Thursday that they have begun a clinical trial on a gene therapy to restore light sensitivity in patients with retinitis pigmentosa, a hereditary eye disorder.

Retinitis pigmentosa is a progressive disease in which genetic abnormalities cause damage to the photoreceptor cells that sense light in the retina. The field of vision gradually narrows, causing deteriorating vision and even blindness. More than 2 million patients are estimated worldwide.

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