TOKYO -- Japan's Takeda Pharmaceutical is reducing jobs on both sides of the Pacific, signaling more layoffs in the U.S. last week and offering buyouts to employees in Japan this week as it struggles under a sluggish stock price and profit margin.
Takeda plans to lay off about 80 employees by the end of March, a Worker Adjustment and Retraining Notification filed in the northeastern state of Massachusetts shows. The company had previously said it would lay off or transfer roughly 800 workers in Massachusetts and about 300 in California.








