ArrowArtboardCreated with Sketch.Title ChevronTitle ChevronIcon FacebookIcon LinkedinIcon Mail ContactPath LayerIcon MailPositive ArrowIcon PrintIcon Twitter
Science

Japan makes strides toward stem cell therapy

OSAKA -- Japanese researchers report taking their first steps toward possible stem-cell-based treatments for muscular dystrophy.

     A Kyoto University team and chemical company Asahi Kasei created skeletal muscle stem cells from induced pluripotent stem cells, or iPS cells. These were injected into a leg of a mouse with muscular dystrophy. In the muscle there, researchers detected a protein that kept muscle mass from deteriorating.

     Japan has nearly 30,000 patients with muscular dystrophy.

     The team, led by Kyoto University lecturer Hidetoshi Sakurai, says the stem cells fused with impaired muscles and helped regenerate them. This could lead to a therapy to slow the course of the disease. The researchers hope to ensure safety and effectiveness through testing on dogs and are eventually aiming for clinical trials.

     At the National Center of Neurology and Psychiatry, a research team headed by Shinichi Takeda is also working on muscular dystrophy. The group has developed a cell transplantation technique. Muscle stem cells were created from iPS cells and shaped into globules.

     Globular cells measuring 500 microns were then transplanted into a mouse with muscular dystrophy. Some impaired muscle was restored, according to the researchers. And three weeks later, the muscles were found moving inside the mouse. Takeda's team will also test the technique on dogs as early as next year before launching clinical trials.

     Both teams will make presentations at a Japanese Society for Regenerative Medicine conference opening Thursday in Yokohama.

(Nikkei)

Sponsored Content

About Sponsored Content This content was commissioned by Nikkei's Global Business Bureau.

You have {{numberArticlesLeft}} free article{{numberArticlesLeft-plural}} left this monthThis is your last free article this month

Stay ahead with our exclusives on Asia;
the most dynamic market in the world.

Stay ahead with our exclusives on Asia

Get trusted insights from experts within Asia itself.

Get trusted insights from experts
within Asia itself.

Try 1 month for $0.99

You have {{numberArticlesLeft}} free article{{numberArticlesLeft-plural}} left this month

This is your last free article this month

Stay ahead with our exclusives on Asia; the most
dynamic market in the world
.

Get trusted insights from experts
within Asia itself.

Try 3 months for $9

Offer ends July 31st

Your trial period has expired

You need a subscription to...

  • Read all stories with unlimited access
  • Use our mobile and tablet apps
See all offers and subscribe

Your full access to Nikkei Asia has expired

You need a subscription to:

  • Read all stories with unlimited access
  • Use our mobile and tablet apps
See all offers
NAR on print phone, device, and tablet media

Nikkei Asian Review, now known as Nikkei Asia, will be the voice of the Asian Century.

Celebrate our next chapter
Free access for everyone - Sep. 30

Find out more